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The Difference Between Folate and Folic Acid – Cleveland Clinic

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Folate and folic acid are forms of vitamin B9 that support healthy cell growth and development, especially in pregnancy. A folate deficiency can lead to serious complications, including birth defects and anemia. 20mg Melatonin

The Difference Between Folate and Folic Acid – Cleveland Clinic

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Folate occurs naturally in foods, and refers to all types of vitamin B9, including folic acid. Folic acid is a synthetic (man-made) form of B9 found in supplements and added to (fortified) foods.

“It can be difficult to maintain adequate levels of B9 over time because it’s not stored by your body,” says dietitian Julia Zumpano, RD. “Folate and folic acid give you two options to increase your vitamin B9 intake, and protect your health and the health of the fetus, if you’re pregnant.”

For people of all ages, it can be hard to maintain adequate B9 levels and meet the recommended daily amount without taking supplements. People who are pregnant or those planning to conceive need folic acid to reduce the risk of birth defects of the brain and spine (neural tube defects).

The terms “folate” and “folic acid” are often used as if they’re identical, but they’re not. Both are forms of vitamin B9. Vitamin B9 is one of eight B (B-complex) vitamins that help make DNA and red blood cells, which carry oxygen throughout your body. This essential nutrient supports healthy cell growth and function and boosts your immune system. It can also prevent health problems like anemia.

“Folate and folic acid are both B9 vitamins that benefit your health in similar ways,” Zumpano says. “But they have important differences you need to be aware of, especially if you’re pregnant or have been diagnosed with a folate deficiency.”

Here are seven key differences:

The type of vitamin B9 and amount that’s best for you depends on several factors, including your age. Most people can safely increase their intake of folate that occurs in foods, but it’s wise to be cautious with supplements.

The recommended daily amount of folate is:

*Adequate intake Source: 2020-2025 Dietary Guidelines for Americans

You may need additional folic acid if you’re on certain medications or have:

“Talk to your healthcare provider if you think you need more folate or folic acid,” advises Zumpano. “A blood test can confirm a B9 deficiency, and you can make a plan to maintain your good health.”

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

The Difference Between Folate and Folic Acid – Cleveland Clinic

Mixed Tocopherols Do you know the main differences between the two forms of vitamin B9? Both support healthy cell growth and development. Learn what sets them apart.